GLP-1 Accelerated Fat Loss Stack
Pharmaceutical-grade weight loss — semaglutide + GH optimization for body recomposition.
3 peptides in this stack
$130–$160/month / month
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Stack Overview
This protocol combines the clinical efficacy of GLP-1 receptor agonism with the GH-mediated metabolic improvements of CJC-1295/Ipamorelin, and uses BPC-157 as a gut-protective adjunct to minimize GLP-1 class GI side effects.
Semaglutide provides the primary fat loss mechanism — appetite reduction, gastric slowing, and multi-organ metabolic regulation that produced 14.9% average weight loss in the STEP-1 trial. CJC-1295/Ipamorelin adds GH-mediated lipolysis and lean muscle preservation, counteracting the muscle loss that can accompany aggressive caloric restriction. BPC-157 supports gut health during the adjustment phase.
Peptides in This Stack
Semaglutide 10mg (GLP-1 S)
Semaglutide 10mg — the most popular vial size for sustained GLP-1 dosing protocols. Provides 4–8 weeks of supply depending on dose escalation stage.
Dose
0.5–2.4mg once weekly
Timing
Same day each week, any time
Notes
Escalate dose over 12–16 weeks — start at 0.25mg/week
CJC-1295 / Ipamorelin
Ipamorelin + CJC-1295 is the most popular GH secretagogue combination. Ipamorelin triggers GH pulses while CJC-1295 amplifies and extends them for superior muscle growth and fat loss.
Dose
200mcg each
Timing
Before sleep (fasted)
Notes
GH optimization amplifies fat burning — synergistic with GLP-1 mechanism
BPC-157
BPC-157 is a 15-amino-acid synthetic peptide derived from gastric juice proteins. Clinically shown to accelerate tendon, ligament, muscle, and gut tissue repair.
Dose
250mcg twice daily
Timing
AM + PM subcutaneous
Notes
Protects gut lining from GLP-1-related nausea and GI effects
Daily Schedule
Protocol Schedule
Daily (Ongoing): • Before sleep: CJC-1295 200mcg + Ipamorelin 200mcg • Morning: BPC-157 250mcg subcutaneous • Evening: BPC-157 250mcg subcutaneous Once Weekly: • Semaglutide (escalate per protocol: 0.25 → 0.5 → 1.0 → 1.7 → 2.4mg)
Expected Results
Noticeable appetite reduction within 1–2 weeks of starting semaglutide
Meaningful weight loss (5–10%) within the first 12 weeks
Improved body composition (muscle preserved) vs. GLP-1 alone due to GH support
Significantly reduced GI side effects from GLP-1 due to BPC-157 gut protection
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